By Tzvi Tzfira Ph.D., Vitaly Citovsky Ph.D. (auth.)
Nuclear Import and Export in crops and Animals presents perception into the outstanding mechanisms of nuclear import and export. This ebook covers quite a number issues from the nuclear pore constitution, to nuclear import and export of macromolecules in plant and animal cells. additionally, the ebook covers the unique situations of nuclear import of Agrobacterium T-DNA in the course of plant genetic transformation, nuclear import and export of animal viruses, and nuclear consumption of international DNA. A bankruptcy on examine the right way to research nuclear delivery concludes the ebook.
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Nuclear Import and Export in crops and Animals offers perception into the notable mechanisms of nuclear import and export. This e-book covers more than a few themes from the nuclear pore constitution, to nuclear import and export of macromolecules in plant and animal cells. furthermore, the publication covers the detailed circumstances of nuclear import of Agrobacterium T-DNA in the course of plant genetic transformation, nuclear import and export of animal viruses, and nuclear consumption of overseas DNA.
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Extra resources for Nuclear Import and Export in Plants and Animals
Importin beta contains a COOH-terminal nucleoporin binding region important for nuclear transport. J Cell Biol 2003; 162:391-401. 215. Bednenko J, Cingolani G, Gerace L. Nucleocytoplasmic transport: Navigating the channel. Traffic 2003; 4:127-35. 216. Schwoebel ED, Talcott B, Cushman I et al. Ran-dependent signal-mediated nuclear import does not require GTP hydrolysis by Ran. J Biol Chem 1998; 273:35170-5. 217. Schwoebel ED, Ho TH, Moore MS. The mechanism of inhibition of Ran-dependent nuclear transport by cellular ATP depletion.
Instead, it investigates the information presendy available about signals involved in the intranuclear targeting of proteins, either to the nuclear matrix or to specific subnuclear domains. Of the several arguments that can be made for the functional importance of specific subnuclear protein targeting—and a role for the nuclear matrix in that targeting—three points will be discussed here. First, several proteins have been found to contain specific signals for their association with the nuclear matrix or for their targeting to specific subnuclear sites.
Architecture and design of the nuclear pore complex. Cell 1992; 69:1133-41. 84. Akey CW, Radermacher M. Architecture of the Xenopus nuclear pore complex revealed by three-dimensional cryo-electron microscopy. J Cell Biol 1993; 122:1-19. 85. Akey CW. Structural plasticity of the nuclear pore complex. J Mol Biol 1995; 248:273-93. 86. Stoffler D, Feja B, Fahrenkrog B et al. Cryo-electron tomography provides novel insights into nuclear pore architecture: Implications for nucleocytoplasmic transport.